Assay Detail
Functional
CHEMBL911112
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Antimalarial activity against Plasmodium falciparum NF54 3D7 after 48 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design and synthesis of potent inhibitors of the malaria parasite dihydroorotate dehydrogenase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.58 | 5.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL218467 | — | — | 1 | 5.75 |
| CHEMBL218703 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL218467 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL218703 | — | IC50 | = | 4000.0 | nM | 5.40 |