Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL911387

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against murine B16 cells by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Mus musculus
Cell Type B16
Confidence 1 — Organism
Curated By Autocuration

Target

B16 (CHEMBL381)
Type CELL-LINE
Organism Mus musculus

Publication

Metabolites from the Lichen Ochrolechia parella growing under two different heliotropic conditions.
Millot M, Tomasi S, Articus K, Rouaud I, Bernard A, Boustie J.
J Nat Prod (2007) 70 : 316 -318
PubMed 17256903 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 5.13 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL53463 DOXORUBICIN 4.0 1 7.00
CHEMBL426543 1 4.99
CHEMBL220486 VARIOLARIC ACID 1 4.41
CHEMBL434750 ERGOSTEROL PEROXIDE 1 4.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL53463 DOXORUBICIN IC50 = 100.0 nM 7.00
CHEMBL426543 IC50 = 10300.0 nM 4.99
CHEMBL220486 VARIOLARIC ACID IC50 = 38700.0 nM 4.41
CHEMBL434750 ERGOSTEROL PEROXIDE IC50 = 77900.0 nM 4.11