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Assay Detail

CHEMBL911869

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiangiogenic activity in HUVEC by chemotaxis assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HUVEC
Confidence 1 — Organism
Curated By Autocuration

Target

HUVEC (CHEMBL613979)
Type CELL-LINE
Organism Homo sapiens

Publication

2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity.
Leese MP, Leblond B, Smith A, Newman SP, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ, Potter BV.
J Med Chem (2006) 49 : 7683 -7696
PubMed 17181151 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.40 6.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL218382 1 6.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL218382 IC50 = 400.0 nM 6.40