Assay Detail
Binding
CHEMBL911872
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Inhibition of human CA2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.69 | 7.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL122708 | EMATE | — | 1 | 7.38 |
| CHEMBL218382 | — | — | 1 | 6.42 |
| CHEMBL374721 | — | — | 1 | 6.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL122708 | EMATE | IC50 | = | 42.0 | nM | 7.38 |
| CHEMBL218382 | — | IC50 | = | 379.0 | nM | 6.42 |
| CHEMBL374721 | — | IC50 | = | 526.0 | nM | 6.28 |