Assay Detail
Binding
CHEMBL912673
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]iloprost from cloned human PGI2 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Replacing the cyclohexene-linker of FR181157 leading to novel IP receptor agonists: orally active prostacyclin mimetics. Part 6.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.17 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL132589 | — | — | 1 | 7.22 |
| CHEMBL439357 | — | — | 1 | 7.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL132589 | — | Ki | = | 60.0 | nM | 7.22 |
| CHEMBL439357 | — | Ki | = | 76.0 | nM | 7.12 |