Assay Detail
Binding
CHEMBL913188
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]colchicine from tubulin in bovine brain at 500 nM
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Potent antitubulin tumor cell cytotoxins based on 3-aroyl indazoles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 1 | - | - |
| IC50 | 1 | 6.30 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL374257 | — | — | 2 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL374257 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL374257 | — | Activity | = | 70.0 | % | - |