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Assay Detail

CHEMBL913191

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of bovine tubulin polymerization
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Potent antitubulin tumor cell cytotoxins based on 3-aroyl indazoles.
Duan JX, Cai X, Meng F, Lan L, Hart C, Matteucci M.
J Med Chem (2007) 50 : 1001 -1006
PubMed 17286393 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.22 5.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL374257 1 5.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL374257 IC50 = 6000.0 nM 5.22