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Assay Detail

CHEMBL913244

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human recombinant caspase 7
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Caspase-7 (CHEMBL3468)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis.
Zhou D, Chu W, Rothfuss J, Zeng C, Xu J, Jones L, Welch MJ, Mach RH.
Bioorg Med Chem Lett (2006) 16 : 5041 -5046
PubMed 16891117 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.63 7.63

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL213759 1 7.63

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL213759 IC50 = 23.5 nM 7.63