Assay Detail
Binding
CHEMBL913595
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of 20 nM AmpC beta lactamase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Interpreting steep dose-response curves in early inhibitor discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.72 | 4.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL375228 | TETRAIODOPHENOLPHTHALEINE | — | 1 | 4.72 |
| CHEMBL429694 | CONGO RED | -1.0 | 1 | - |
| CHEMBL34241 | ROTTLERIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL375228 | TETRAIODOPHENOLPHTHALEINE | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL429694 | CONGO RED | IC50 | - | — | - | |
| CHEMBL34241 | ROTTLERIN | IC50 | - | — | - |