Assay Detail
Binding
CHEMBL914609
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HCV NS3 serine protease
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepatitis C virus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Prediction of binding for a kind of non-peptic HCV NS3 serine protease inhibitors from plants by molecular docking and MM-PBSA method.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.84 | 6.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL439549 | — | — | 1 | 6.18 |
| CHEMBL436991 | — | — | 1 | 6.17 |
| CHEMBL225624 | — | — | 1 | 6.00 |
| CHEMBL389895 | — | — | 1 | 5.00 |
| CHEMBL224536 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL439549 | — | IC50 | = | 660.0 | nM | 6.18 |
| CHEMBL436991 | — | IC50 | = | 680.0 | nM | 6.17 |
| CHEMBL225624 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL389895 | — | IC50 | = | 10090.0 | nM | 5.00 |
| CHEMBL224536 | — | IC50 | = | 949700.0 | nM | - |