Assay Detail
Binding
CHEMBL915594
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [32P]S1P from human S1P1 receptor expressed in HEK293T cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK-293T |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.52 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL389033 | — | — | 1 | 7.52 |
| CHEMBL227371 | — | — | 1 | 7.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL389033 | — | Ki | = | 30.0 | nM | 7.52 |
| CHEMBL227371 | — | Ki | = | 30.0 | nM | 7.52 |