Assay Detail
Functional
CHEMBL917068
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Inhibition of microsome protein secretion in Toxoplasma gondii 2F1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Toxoplasma gondii |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Cysteine protease inhibitors block Toxoplasma gondii microneme secretion and cell invasion.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.45 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL222649 | — | — | 1 | 4.60 |
| CHEMBL374858 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL222649 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL374858 | — | IC50 | = | 50000.0 | nM | 4.30 |