Assay Detail
Binding
CHEMBL917712
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Binding affinity to rabbit bradykinin B1 receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
2,3-diaminopyridine bradykinin B1 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 8.52 | 9.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL225607 | — | — | 1 | 9.16 |
| CHEMBL221998 | — | — | 1 | 8.96 |
| CHEMBL222038 | — | — | 1 | 8.57 |
| CHEMBL387638 | — | — | 1 | 8.52 |
| CHEMBL221984 | — | — | 1 | 7.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL225607 | — | Ki | = | 0.69 | nM | 9.16 |
| CHEMBL221998 | — | Ki | = | 1.1 | nM | 8.96 |
| CHEMBL222038 | — | Ki | = | 2.7 | nM | 8.57 |
| CHEMBL387638 | — | Ki | = | 3.0 | nM | 8.52 |
| CHEMBL221984 | — | Ki | = | 41.5 | nM | 7.38 |