Assay Detail
Functional
CHEMBL918333
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Toxoplasma gondii RH replication in human foreskin fibroblasts incubated for 24 hrs with drug after 2 hrs postinfection by immunofluorescence microscopy
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Toxoplasma gondii |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Growth inhibition of Toxoplasma gondii and Plasmodium falciparum by nanomolar concentrations of 1-hydroxy-2-dodecyl-4(1H)quinolone, a high-affinity inhibitor of alternative (type II) NADH dehydrogenases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.62 | 8.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL224182 | — | — | 1 | 8.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL224182 | — | IC50 | = | 2.4 | nM | 8.62 |