Assay Detail
Functional
CHEMBL918577
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against variola virus BUT virus by CPE assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Variola virus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
N-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1H)-yl)carboxamides: Identification of novel orthopoxvirus egress inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 6.82 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL375768 | — | — | 1 | 8.00 |
| CHEMBL220610 | — | — | 1 | 7.70 |
| CHEMBL221054 | — | — | 1 | 7.70 |
| CHEMBL220150 | — | — | 1 | 6.66 |
| CHEMBL219691 | — | — | 1 | 5.85 |
| CHEMBL220098 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL375768 | — | EC50 | = | 10.0 | nM | 8.00 |
| CHEMBL220610 | — | EC50 | = | 20.0 | nM | 7.70 |
| CHEMBL221054 | — | EC50 | = | 20.0 | nM | 7.70 |
| CHEMBL220150 | — | EC50 | = | 220.0 | nM | 6.66 |
| CHEMBL219691 | — | EC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL220098 | — | EC50 | = | 10000.0 | nM | 5.00 |