Assay Detail
Binding
CHEMBL918773
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Binding affinity at amyloid peptide plaques
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and characterization of styrylchromone derivatives as beta-amyloid imaging agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.77 | 8.06 |
| Ki | 1 | 7.82 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL388577 | — | — | 1 | 8.06 |
| CHEMBL71696 | — | — | 1 | 7.82 |
| CHEMBL224541 | — | — | 1 | 7.76 |
| CHEMBL224490 | — | — | 1 | 7.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL388577 | — | Kd | = | 8.7 | nM | 8.06 |
| CHEMBL71696 | — | Ki | = | 15.0 | nM | 7.82 |
| CHEMBL224541 | — | Kd | = | 17.5 | nM | 7.76 |
| CHEMBL224490 | — | Kd | = | 32.0 | nM | 7.50 |