Assay Detail
ADMET
CHEMBL918816
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Cytotoxicity against human PC3 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
In vitro cytotoxicity evaluation of some substituted isatin derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.37 | 4.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL376616 | — | — | 1 | 4.59 |
| CHEMBL388580 | — | — | 1 | 4.39 |
| CHEMBL387839 | — | — | 1 | 4.14 |
| CHEMBL388579 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL376616 | — | IC50 | = | 25900.0 | nM | 4.59 |
| CHEMBL388580 | — | IC50 | = | 41000.0 | nM | 4.39 |
| CHEMBL387839 | — | IC50 | = | 71900.0 | nM | 4.14 |
| CHEMBL388579 | — | IC50 | = | 101000.0 | nM | - |