Assay Detail
Functional
CHEMBL920537
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Effect on cell growth in A549 cells by MTS assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Identification of novel and improved antimitotic agents derived from noscapine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.72 | 9.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL159 | VINBLASTINE | 4.0 | 1 | 9.05 |
| CHEMBL376130 | — | — | 1 | 7.01 |
| CHEMBL224797 | — | — | 1 | 6.22 |
| CHEMBL364713 | NOSCAPINE | 2.0 | 1 | 4.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL159 | VINBLASTINE | EC50 | = | 0.9 | nM | 9.05 |
| CHEMBL376130 | — | EC50 | = | 97.0 | nM | 7.01 |
| CHEMBL224797 | — | EC50 | = | 600.0 | nM | 6.22 |
| CHEMBL364713 | NOSCAPINE | EC50 | = | 25000.0 | nM | 4.60 |