Assay Detail
Binding
CHEMBL920546
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Binding affinity to HCV 40-mer RNA by MS based binding assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepacivirus hominis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
SAR by MS: discovery of a new class of RNA-binding small molecules for the hepatitis C virus: internal ribosome entry site IIA subdomain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 5.64 | 6.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL223720 | — | — | 1 | 6.14 |
| CHEMBL223608 | — | — | 1 | 6.07 |
| CHEMBL388502 | — | — | 1 | 5.77 |
| CHEMBL224788 | — | — | 1 | 5.46 |
| CHEMBL224999 | — | — | 1 | 4.77 |
| CHEMBL427101 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL223720 | — | Kd | = | 720.0 | nM | 6.14 |
| CHEMBL223608 | — | Kd | = | 860.0 | nM | 6.07 |
| CHEMBL388502 | — | Kd | = | 1700.0 | nM | 5.77 |
| CHEMBL224788 | — | Kd | = | 3500.0 | nM | 5.46 |
| CHEMBL224999 | — | Kd | = | 17000.0 | nM | 4.77 |
| CHEMBL427101 | — | Kd | > | 100000.0 | nM | - |