Assay Detail
Binding
CHEMBL920798
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Displacement of [3H]KA from kainate receptor in rat synaptosomes
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A tetrazolyl-substituted subtype-selective AMPA receptor agonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.96 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL370038 | — | — | 1 | 4.96 |
| CHEMBL13378 | (R,S)-AMPA | — | 1 | - |
| CHEMBL388746 | — | — | 1 | - |
| CHEMBL227922 | — | — | 1 | - |
| CHEMBL193087 | — | — | 1 | - |
| CHEMBL372643 | — | — | 1 | - |
| CHEMBL370941 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL370038 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL13378 | (R,S)-AMPA | IC50 | > | 100000.0 | nM | - |
| CHEMBL388746 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL227922 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL193087 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL372643 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL370941 | — | IC50 | > | 100000.0 | nM | - |