Assay Detail
Functional
CHEMBL920802
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at GluR2 L483Y mutant expressed in Xenopus laevis oocytes assessed as by effect on glutamate-induced current by two-electrode voltage clamp assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Oocyte |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A tetrazolyl-substituted subtype-selective AMPA receptor agonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 4.02 | 4.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL388746 | — | — | 1 | 4.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL388746 | — | EC50 | = | 95000.0 | nM | 4.02 |