Assay Detail
Functional
CHEMBL921747
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human A549 cells after 1 hr by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Inhibitors of DNA polymerase beta: activity and mechanism.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.43 | 5.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL269277 | BETULINIC ACID | 1.0 | 1 | 5.18 |
| CHEMBL259025 | EDGEWORIN | — | 1 | 4.10 |
| CHEMBL400247 | STIGMASTEROL | — | 1 | 4.01 |
| CHEMBL168 | OLEANOLIC_ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL269277 | BETULINIC ACID | IC50 | = | 6650.0 | nM | 5.18 |
| CHEMBL259025 | EDGEWORIN | IC50 | = | 80200.0 | nM | 4.10 |
| CHEMBL400247 | STIGMASTEROL | IC50 | = | 98200.0 | nM | 4.01 |
| CHEMBL168 | OLEANOLIC_ACID | IC50 | > | 100000.0 | nM | - |