Assay Detail
Binding
CHEMBL921755
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]JV1-42 from GHRH receptor expressed in human MX1 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | MX1 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Growth hormone-releasing hormone receptor (CHEMBL2032) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Potentiation of mammary cancer inhibition by combination of antagonists of growth hormone-releasing hormone with docetaxel.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.85 | 9.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3545252 | DOCETAXEL | 4.0 | 1 | 9.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3545252 | DOCETAXEL | IC50 | = | 0.14 | nM | 9.85 |