Assay Detail
Binding
CHEMBL921801
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human COX2 preincubated before addition of [1-14C]arachidonic acid
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Molecular determinants for the selective inhibition of cyclooxygenase-2 by lumiracoxib.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.21 | 6.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL404108 | LUMIRACOXIB | 4.0 | 1 | 6.50 |
| CHEMBL259218 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL404108 | LUMIRACOXIB | Ki | = | 320.0 | nM | 6.50 |
| CHEMBL259218 | — | Ki | = | 1200.0 | nM | 5.92 |