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Assay Detail

CHEMBL922325

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of adrenergic alpha 1 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis and structure-affinity relationships of novel spirocyclic sigma receptor ligands with furopyrazole structure.
Schläger T, Schepmann D, Würthwein EU, Wünsch B.
Bioorg Med Chem (2008) 16 : 2992 -3001
PubMed 18221879 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.91 5.91

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL259732 1 5.91
CHEMBL410832 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL259732 IC50 = 1218.0 nM 5.91
CHEMBL410832 IC50 > 1000.0 nM -