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Assay Detail

CHEMBL922470

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of glucagon-stimulated glycogenolysis in Wistar rat hepatocytes assessed as glucose release after 90 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Cell Type Hepatocyte
Confidence 1 — Organism
Curated By Autocuration

Target

Hepatocyte (CHEMBL613362)
Type CELL-LINE
Organism Rattus norvegicus

Publication

Effect of five-membered sugar mimics on mammalian glycogen-degrading enzymes and various glucosidases.
Minami Y, Kuriyama C, Ikeda K, Kato A, Takebayashi K, Adachi I, Fleet GW, Kettawan A, Okamoto T, Asano N.
Bioorg Med Chem (2008) 16 : 2734 -2740
PubMed 18258441 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL80254 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL80254 IC50 = 1000.0 nM 6.00