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Assay Detail

CHEMBL922540

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of PKA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Pyrazolo-pyrimidines: a novel heterocyclic scaffold for potent and selective p38 alpha inhibitors.
Das J, Moquin RV, Pitt S, Zhang R, Shen DR, McIntyre KW, Gillooly K, Doweyko AM, Sack JS, Zhang H, Kiefer SE, Kish K, McKinnon M, Barrish JC, Dodd JH, Schieven GL, Leftheris K.
Bioorg Med Chem Lett (2008) 18 : 2652 -2657
PubMed 18359226 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.34 4.34

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL259922 1 4.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL259922 IC50 = 46000.0 nM 4.34