Assay Detail

CHEMBL922929

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Functional

Inhibition of anthrax lethal factor induced J774A.1 cell death by MTT assay

ChEMBL ↗

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Target

J774.A1 (CHEMBL614040) ↗

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J774.A1 (CHEMBL614040) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target J774.A1

CHEMBL614040

Anchored from Assay target.

Protein identity J774.A1

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Mus musculus
Cell Type	J774.A1
Confidence	1 — Organism
Curated By	Autocuration

Target

J774.A1 (CHEMBL614040) ↗

Type	CELL-LINE
Organism	Mus musculus

Publication

Inhibitors of anthrax lethal factor.

Gaddis BD, Avramova LV, Chmielewski J.
Bioorg Med Chem Lett (2007) 17 : 4575 -4578
PubMed 17574849 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.30	5.30

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL250711	OLEOYL DOPAMINE	—	1	5.30

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL250711	OLEOYL DOPAMINE	IC50	=	5000.0	nM	5.30