Assay Detail
Binding
CHEMBL922930
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Inhibition of anthrax lethal factor by FRET assay
7
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacillus anthracis |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Inhibitors of anthrax lethal factor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.59 | 4.89 |
| Ki | 3 | 5.50 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL251733 | — | — | 2 | 5.77 |
| CHEMBL250711 | OLEOYL DOPAMINE | — | 2 | 5.52 |
| CHEMBL251734 | — | — | 2 | 5.22 |
| CHEMBL399925 | — | — | 1 | 4.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL251733 | — | Ki | = | 1700.0 | nM | 5.77 |
| CHEMBL250711 | OLEOYL DOPAMINE | Ki | = | 3000.0 | nM | 5.52 |
| CHEMBL251734 | — | Ki | = | 6000.0 | nM | 5.22 |
| CHEMBL251733 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL250711 | OLEOYL DOPAMINE | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL251734 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL399925 | — | IC50 | = | 70000.0 | nM | 4.16 |