Assay Detail
Functional
CHEMBL923030
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Cytotoxicity against human PC3 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
N-phenethyl and N-naphthylmethyl isatins and analogues as in vitro cytotoxic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.71 | 5.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL406943 | — | — | 1 | 5.84 |
| CHEMBL406631 | — | — | 1 | 5.68 |
| CHEMBL406207 | — | — | 1 | 5.66 |
| CHEMBL260493 | — | — | 1 | 5.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL406943 | — | IC50 | = | 1440.0 | nM | 5.84 |
| CHEMBL406631 | — | IC50 | = | 2090.0 | nM | 5.68 |
| CHEMBL406207 | — | IC50 | = | 2210.0 | nM | 5.66 |
| CHEMBL260493 | — | IC50 | = | 2290.0 | nM | 5.64 |