Assay Detail
Binding
CHEMBL923034
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of bovine neuronal tubulin polymerization for 60 mins
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
N-phenethyl and N-naphthylmethyl isatins and analogues as in vitro cytotoxic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.27 | 5.78 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL159 | VINBLASTINE | 4.0 | 1 | 5.78 |
| CHEMBL260493 | — | — | 1 | 5.19 |
| CHEMBL406190 | — | — | 1 | 5.18 |
| CHEMBL406943 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL159 | VINBLASTINE | IC50 | = | 1660.0 | nM | 5.78 |
| CHEMBL260493 | — | IC50 | = | 6470.0 | nM | 5.19 |
| CHEMBL406190 | — | IC50 | = | 6600.0 | nM | 5.18 |
| CHEMBL406943 | — | IC50 | = | 12000.0 | nM | 4.92 |