Assay Detail
Binding
CHEMBL923632
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity at SER3 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | HEK293 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.10 | 7.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53929 | OCTOPAMINE | 2.0 | 1 | 7.62 |
| CHEMBL11608 | TYRAMINE | 3.0 | 1 | 4.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53929 | OCTOPAMINE | EC50 | = | 24.0 | nM | 7.62 |
| CHEMBL11608 | TYRAMINE | EC50 | = | 26000.0 | nM | 4.58 |