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Assay Detail

CHEMBL923886

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rice alpha-glucosidase
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryza sativa
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Effect of five-membered sugar mimics on mammalian glycogen-degrading enzymes and various glucosidases.
Minami Y, Kuriyama C, Ikeda K, Kato A, Takebayashi K, Adachi I, Fleet GW, Kettawan A, Okamoto T, Asano N.
Bioorg Med Chem (2008) 16 : 2734 -2740
PubMed 18258441 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 5.56 5.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL405957 1 5.82
CHEMBL406973 1 5.77
CHEMBL1208974 SALACINOL 1 5.58
CHEMBL259721 1 5.07
CHEMBL80254 1 -
CHEMBL408278 1 -
CHEMBL312653 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL405957 IC50 = 1500.0 nM 5.82
CHEMBL406973 IC50 = 1700.0 nM 5.77
CHEMBL1208974 SALACINOL IC50 = 2600.0 nM 5.58
CHEMBL259721 IC50 = 8600.0 nM 5.07
CHEMBL80254 IC50 = 250000.0 nM -
CHEMBL408278 IC50 = 220000.0 nM -
CHEMBL312653 IC50 = 370000.0 nM -