Assay Detail

CHEMBL923892

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibition of maltase in human Caco-2 cell membrane

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Cell Type	Caco-2
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Effect of five-membered sugar mimics on mammalian glycogen-degrading enzymes and various glucosidases.

Minami Y, Kuriyama C, Ikeda K, Kato A, Takebayashi K, Adachi I, Fleet GW, Kettawan A, Okamoto T, Asano N.
Bioorg Med Chem (2008) 16 : 2734 -2740
PubMed 18258441 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.30	6.30

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1208974	SALACINOL	—	1	6.30

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1208974	SALACINOL	IC50	=	500.0	nM	6.30