Assay Detail
Binding
CHEMBL924749
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HSV1 GAL4-tagged VP16 by luciferase assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis of small molecule inhibitors of the orphan nuclear receptor steroidogenic factor-1 (NR5A1) based on isoquinolinone scaffolds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.62 | 4.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL260419 | — | — | 1 | 4.62 |
| CHEMBL265938 | — | — | 1 | 4.62 |
| CHEMBL408702 | — | — | 1 | - |
| CHEMBL260420 | — | — | 1 | - |
| CHEMBL408947 | — | — | 1 | - |
| CHEMBL412079 | — | — | 1 | - |
| CHEMBL259067 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL260419 | — | IC50 | = | 24100.0 | nM | 4.62 |
| CHEMBL265938 | — | IC50 | = | 24200.0 | nM | 4.62 |
| CHEMBL408702 | — | IC50 | > | 33000.0 | nM | - |
| CHEMBL260420 | — | IC50 | > | 33000.0 | nM | - |
| CHEMBL408947 | — | IC50 | > | 33000.0 | nM | - |
| CHEMBL412079 | — | IC50 | > | 33000.0 | nM | - |
| CHEMBL259067 | — | IC50 | > | 33000.0 | nM | - |