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Assay Detail

CHEMBL924982

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to kappa opioid receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Kappa-type opioid receptor (CHEMBL237)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and evaluation in monkey of two sensitive 11C-labeled aryloxyanilide ligands for imaging brain peripheral benzodiazepine receptors in vivo.
Briard E, Zoghbi SS, Imaizumi M, Gourley JP, Shetty HU, Hong J, Cropley V, Fujita M, Innis RB, Pike VW.
J Med Chem (2008) 51 : 17 -30
PubMed 18067245 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.66 5.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL253597 1 5.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL253597 Ki = 2200.0 nM 5.66