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Assay Detail

CHEMBL925365

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of tubulin polymerization
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Sesquiterpenoids and cytotoxic lignans from the bark of Libocedrus chevalieri.
Zhang YJ, Litaudon M, Bousserouel H, Martin MT, Thoison O, Léonce S, Dumontet V, Sévenet T, Guéritte F.
J Nat Prod (2007) 70 : 1368 -1370
PubMed 17676899 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.18 5.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL292945 1 5.30
CHEMBL398327 1 5.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL292945 IC50 = 5000.0 nM 5.30
CHEMBL398327 IC50 = 9000.0 nM 5.05