Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL925550

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human SK-N-MC cells by MTT assay
29
Total Activities
29
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SK-N-MC
Confidence 1 — Organism
Curated By Autocuration

Target

SK-N-MC (CHEMBL614163)
Type CELL-LINE
Organism Homo sapiens

Publication

Investigating the antiproliferative activity of quinoline-5,8-diones and styrylquinolinecarboxylic acids on tumor cell lines.
Podeszwa B, Niedbala H, Polanski J, Musiol R, Tabak D, Finster J, Serafin K, Milczarek M, Wietrzyk J, Boryczka S, Mol W, Jampilek J, Dohnal J, Kalinowski DS, Richardson DR.
Bioorg Med Chem Lett (2007) 17 : 6138 -6141
PubMed 17904844 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 29 5.37 5.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL388378 1 5.37
CHEMBL202312 1 -
CHEMBL402271 1 -
CHEMBL428230 1 -
CHEMBL249172 1 -
CHEMBL249171 1 -
CHEMBL248968 1 -
CHEMBL402270 1 -
CHEMBL248967 1 -
CHEMBL248966 1 -
CHEMBL402269 1 -
CHEMBL248965 1 -
CHEMBL400150 1 -
CHEMBL248772 1 -
CHEMBL248771 1 -
CHEMBL225640 1 -
CHEMBL248769 1 -
CHEMBL400149 1 -
CHEMBL250670 1 -
CHEMBL250487 1 -
CHEMBL446454 1 -
CHEMBL250486 1 -
CHEMBL241898 1 -
CHEMBL250485 1 -
CHEMBL250484 1 -
CHEMBL224238 1 -
CHEMBL250659 1 -
CHEMBL224482 1 -
CHEMBL248770 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL388378 IC50 = 4260.0 nM 5.37
CHEMBL202312 IC50 - -
CHEMBL402271 IC50 - -
CHEMBL428230 IC50 - -
CHEMBL249172 IC50 - -
CHEMBL249171 IC50 - -
CHEMBL248968 IC50 - -
CHEMBL402270 IC50 - -
CHEMBL248967 IC50 - -
CHEMBL248966 IC50 - -
CHEMBL402269 IC50 - -
CHEMBL248965 IC50 - -
CHEMBL400150 IC50 - -
CHEMBL248772 IC50 - -
CHEMBL248771 IC50 - -
CHEMBL225640 IC50 - -
CHEMBL248769 IC50 - -
CHEMBL400149 IC50 - -
CHEMBL250670 IC50 - -
CHEMBL250487 IC50 - -
CHEMBL446454 IC50 - -
CHEMBL250486 IC50 - -
CHEMBL241898 IC50 > 6250.0 nM -
CHEMBL250485 IC50 - -
CHEMBL250484 IC50 - -
CHEMBL224238 IC50 - -
CHEMBL250659 IC50 - -
CHEMBL224482 IC50 > 6250.0 nM -
CHEMBL248770 IC50 - -