Assay Detail
Functional
CHEMBL925630
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Inhibition of fMLP-induced human PMN migration after 45 mins
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.43 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL249132 | — | — | 1 | 6.66 |
| CHEMBL379761 | — | — | 1 | 6.19 |
| CHEMBL377169 | — | — | 1 | - |
| CHEMBL401314 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL249132 | — | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL379761 | — | IC50 | = | 640.0 | nM | 6.19 |
| CHEMBL377169 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL401314 | — | IC50 | > | 10000.0 | nM | - |