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Assay Detail

CHEMBL925810

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of lymphoid-specific tyrosine phosphatase pLyp35 mutant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases.
Yu X, Sun JP, He Y, Guo X, Liu S, Zhou B, Hudmon A, Zhang ZY.
Proc Natl Acad Sci U S A (2007) 104 : 19767 -19772
PubMed 18056643 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.32 4.32

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL260920 1 4.32

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL260920 IC50 = 48000.0 nM 4.32