Assay Detail
Functional
CHEMBL925840
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Inhibition of inosine and alanine-induced germination of Bacillus anthracis Sterne spore pre-incubated for 15 mins
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Bacillus anthracis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Identification of an in vivo inhibitor of Bacillus anthracis spore germination.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 4.24 | 4.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL388931 | — | — | 1 | 4.51 |
| CHEMBL406852 | — | — | 1 | 4.47 |
| CHEMBL255442 | — | — | 1 | 4.17 |
| CHEMBL244169 | — | — | 1 | 4.06 |
| CHEMBL283078 | THIOGUANOSINE | — | 1 | 4.01 |
| CHEMBL402439 | XANTHOSINE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL388931 | — | Ki | = | 31000.0 | nM | 4.51 |
| CHEMBL406852 | — | Ki | = | 34000.0 | nM | 4.47 |
| CHEMBL255442 | — | Ki | = | 68000.0 | nM | 4.17 |
| CHEMBL244169 | — | Ki | = | 87000.0 | nM | 4.06 |
| CHEMBL283078 | THIOGUANOSINE | Ki | = | 98000.0 | nM | 4.01 |
| CHEMBL402439 | XANTHOSINE | Ki | = | 777000.0 | nM | - |