Assay Detail
Functional
CHEMBL926192
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Cytotoxicity against human OVCAR-3 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | OVCAR-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Improved biochemical strategies for targeted delivery of taxoids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.65 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 9.70 |
| CHEMBL253253 | — | — | 1 | 9.64 |
| CHEMBL438350 | — | — | 1 | 7.70 |
| CHEMBL404914 | — | — | 1 | 7.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | IC50 | = | 0.2 | nM | 9.70 |
| CHEMBL253253 | — | IC50 | = | 0.23 | nM | 9.64 |
| CHEMBL438350 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL404914 | — | IC50 | = | 27.0 | nM | 7.57 |