Assay Detail
Binding
CHEMBL927100
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Inhibition of dopamine D2 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
(Phenylpiperazinyl-butyl)oxindoles as selective 5-HT7 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.17 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL411663 | — | — | 1 | 6.48 |
| CHEMBL409662 | — | — | 1 | 6.02 |
| CHEMBL260994 | — | — | 1 | 6.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL411663 | — | Ki | = | 330.0 | nM | 6.48 |
| CHEMBL409662 | — | Ki | = | 950.0 | nM | 6.02 |
| CHEMBL260994 | — | Ki | = | 960.0 | nM | 6.02 |