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Assay Detail

CHEMBL928494

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Functional
Antioxidant activity assessed as DPPH radical scavenging activity
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Publication

Synthesis and antioxidant activities of 3,5-dialkoxy-4-hydroxycinnamamides.
Kang TS, Jo HO, Park WK, Kim JP, Konishi Y, Kong JY, Park NS, Jung YS.
Bioorg Med Chem Lett (2008) 18 : 1663 -1667
PubMed 18249541 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 12 4.13 4.18

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL253648 1 4.18
CHEMBL253011 1 4.17
CHEMBL253872 1 4.17
CHEMBL400555 1 4.16
CHEMBL254072 1 4.14
CHEMBL254073 1 4.12
CHEMBL252807 1 4.11
CHEMBL254070 1 4.09
CHEMBL253649 1 4.07
CHEMBL252604 1 4.07
CHEMBL399863 1 -
CHEMBL254274 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL253648 IC50 = 66600.0 nM 4.18
CHEMBL253011 IC50 = 68400.0 nM 4.17
CHEMBL253872 IC50 = 67700.0 nM 4.17
CHEMBL400555 IC50 = 69000.0 nM 4.16
CHEMBL254072 IC50 = 73000.0 nM 4.14
CHEMBL254073 IC50 = 75600.0 nM 4.12
CHEMBL252807 IC50 = 77700.0 nM 4.11
CHEMBL254070 IC50 = 80300.0 nM 4.09
CHEMBL253649 IC50 = 85100.0 nM 4.07
CHEMBL252604 IC50 = 84400.0 nM 4.07
CHEMBL399863 IC50 = 176800.0 nM -
CHEMBL254274 IC50 = 114100.0 nM -