Assay Detail
Functional
CHEMBL928707
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Antitumor activity against human A549 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Leishmanicidal and trypanocidal activities of 2-aminocyclohexanol and 1,2-cyclohexanediamine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.76 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL254735 | — | — | 1 | 4.96 |
| CHEMBL254329 | — | — | 1 | 4.85 |
| CHEMBL254532 | — | — | 1 | 4.63 |
| CHEMBL254940 | — | — | 1 | 4.60 |
| CHEMBL254733 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL254735 | — | IC50 | = | 10900.0 | nM | 4.96 |
| CHEMBL254329 | — | IC50 | = | 14200.0 | nM | 4.85 |
| CHEMBL254532 | — | IC50 | = | 23400.0 | nM | 4.63 |
| CHEMBL254940 | — | IC50 | = | 25200.0 | nM | 4.60 |
| CHEMBL254733 | — | IC50 | > | 25700.0 | nM | - |