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Assay Detail

CHEMBL928992

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Binding
Binding affinity at human ERG
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Intermediate

Publication

Synthesis of N-pyrimidinyl-2-phenoxyacetamides as adenosine A2A receptor antagonists.
Zhang X, Rueter JK, Chen Y, Moorjani M, Lanier MC, Lin E, Gross RS, Tellew JE, Williams JP, Lechner SM, Markison S, Joswig T, Malany S, Santos M, Castro-Palomino JC, Crespo MI, Prat M, Gual S, Díaz JL, Saunders J, Slee DH.
Bioorg Med Chem Lett (2008) 18 : 1778 -1783
PubMed 18329269 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.75 6.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL256755 1 6.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL256755 Ki = 180.0 nM 6.75