Assay Detail
Binding
CHEMBL929612
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of pig kidney cytosolic leucine aminopeptidase
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Individual stereoisomers of phosphinic dipeptide inhibitor of leucine aminopeptidase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.43 | 7.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL254284 | — | — | 1 | 7.35 |
| CHEMBL327844 | — | — | 1 | 7.18 |
| CHEMBL252204 | — | — | 1 | 6.57 |
| CHEMBL393949 | — | — | 1 | 6.00 |
| CHEMBL254285 | — | — | 1 | 5.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL254284 | — | Ki | = | 45.0 | nM | 7.35 |
| CHEMBL327844 | — | Ki | = | 66.0 | nM | 7.18 |
| CHEMBL252204 | — | Ki | = | 271.0 | nM | 6.57 |
| CHEMBL393949 | — | Ki | = | 988.0 | nM | 6.00 |
| CHEMBL254285 | — | Ki | = | 8800.0 | nM | 5.06 |