Assay Detail
Functional
CHEMBL930508
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ADP-induced P-selectin expression in human platelets
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Platelet |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
P2Y1 receptor antagonists as novel antithrombotic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.34 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL255095 | — | — | 1 | 6.82 |
| CHEMBL258406 | — | — | 1 | 6.40 |
| CHEMBL255306 | — | — | 1 | 6.24 |
| CHEMBL255307 | — | — | 1 | 6.20 |
| CHEMBL255308 | — | — | 1 | 6.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL255095 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL258406 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL255306 | — | IC50 | = | 580.0 | nM | 6.24 |
| CHEMBL255307 | — | IC50 | = | 630.0 | nM | 6.20 |
| CHEMBL255308 | — | IC50 | = | 880.0 | nM | 6.06 |