Assay Detail
Functional
CHEMBL930901
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against RSV R2LO replication in HeLa cells
3
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Respiratory syncytial virus |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Respiratory syncytial virus (CHEMBL612679) ↗| Type | ORGANISM |
| Organism | Respiratory syncytial virus |
Publication
Selection of a respiratory syncytial virus fusion inhibitor clinical candidate. 2. Discovery of a morpholinopropylaminobenzimidazole derivative (TMC353121).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.30 | 6.30 |
| pEC90 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL408963 | — | — | 3 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL408963 | — | EC50 | = | 501.19 | nM | 6.30 |
| CHEMBL408963 | — | EC50 | = | 0.2799 | ug.mL-1 | - |
| CHEMBL408963 | — | pEC90 | < | 4.0 | — | - |