Assay Detail
Binding
CHEMBL931201
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Staphylococcus aureus FabH assessed as reduced accumulation of long chain beta-ketoacyl-ACP by FabF/FabH PAGE elongation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Staphylococcus aureus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.04 | 5.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1092943 | PLATENCIN | — | 1 | 5.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1092943 | PLATENCIN | IC50 | = | 9170.0 | nM | 5.04 |